Acromegaly-is a syndrom resulted when the pituitary gland produces excess growth hormone after epiphyseal plate closure at puberty.
Acromegaly most commonly affects adults in middle age(20-40 years) evolves gradual,has a course slowly progressive and can result in severe disfigurements at the level of:
1.Head and Face
-big skull with enlogated face
-big ears,big nose,lips and tongue
-prominent frontal bosses and prominent supraprbital ridge.
2.Hands:
-big hands with blunt fingers
3.Skeletal Affection:
-osteoarthritis may occur
4.Skin Affection:
-thick
-wrinkled
-greasy
5.Internal Organs Enlargement
Neurological Manifestation:
-peripherial neuropathy
-parasthesias in hands and feet may occur
-pressure manifestations