The causes are not definitly known,but certain risk factors ,precancerous conditions and host variables are known to influence susceptibility of breast cancer.
Risk factors:
1.Hormonal Disturbance:endogenous and exogenous.Increased estrogen,progesteron and prolactin.
2.Contraceptive pill:proper use is safe (not precancerous or risky).Under certain circumstances oral contraceptive may be potentially risky for development of breast cancer:
-continued,not interrupted,oral contraceptive for long time:years undefined,may be more than 4.
-practice of oral contraceptive over 35 years of age,may be also risky.
3.Parity (full term pregnancy):
-multiparas (women with many pregnancies) are exposed to more incidence of breast cancer,that usually appears in 40-60 years,specially when regular breast-feeding is not fallowed.
-mother that don't practice breast feeding are exposed to milk retention,and is risk to breast cancer.
-wemen that never gived birth to babies are more at risk.
-wemen having there first full term pregnancy at older age,specially after 35 may also show somewhat higher incidence of breast cancer.
4.Menstruation Pattern:
Early menanche (under 12) and late natural menopause (after 50) are associated with little increased incidence.
Late menanche and early menopause are associated with lower incidence.
5.Family history of breast cancer:
Family having cases of breast cancer show higher incidence of disease.The more intimate the degree of relation,more risk is.
Cancer at one breast increases susceptibility to involvement of the other breast.
Cases of cancer body uterus show more incidence of breast cancer and case of breast cancer show increased endometrial cancer.
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